Architected Lattices with a Topological Transition
This article develops topological metamaterials showing multidirectional two‐step deformation under compression by embedding contact‐enabled topological mechanisms into lattice structures. Experiments on 3D‐printed 2D and 3D lattices and finite element simulations are conducted to demonstrate the working principle of the topological metamaterials.
Shivam Agarwal, Lihua Jin
wiley +1 more source
Multiple solutions for a critical $p(x)$-Kirchhoff type equations
In this paper, by using the concentration--compactness principle of Lions for variable exponents and variational arguments, we obtain the existence and multiplicity solutions for a class of $p(x)$-Kirchhoff type equations with critical exponent.
Najib Tsouli+2 more
doaj +1 more source
Uncertainty principles for the windowed Hankel transform [PDF]
The aim of this paper is to prove some new uncertainty principles for the windowed Hankel transform. They include uncertainty principle for orthonormal sequence, local uncertainty principle, logarithmic uncertainty principle and Heisenberg-type uncertainty principle.
arxiv +1 more source
Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones
Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley +1 more source
The concentration-compactness principles for W s,p(·,·)(ℝ N ) and application [PDF]
Abstract We obtain a critical imbedding and then, concentration-compactness principles for fractional Sobolev spaces with variable exponents. As an application of these results, we obtain the existence of many solutions for a class of critical nonlocal problems with variable exponents, which is even new for constant exponent case.
Ky Ho, Yun-Ho Kim
openaire +3 more sources
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source
Generalized Concentration-Compactness Principles for Variable Exponent Lebesgue Spaces with Asymptotic Analysis of Low Energy Extremals [PDF]
In this paper, we prove two generalized concentration-compactness principles for variable exponent Lebesgue spaces and as an application study the asymptotic behaviour of low energy extremals.
Zia Bashir+3 more
openaire +3 more sources
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring+6 more
wiley +1 more source
On the Complementarity Principle and the Uncertainty Principle [PDF]
We present a scheme in which we investigate the two-slit experiment and we show that the principle of complementarity is more fundamental then the uncertainty principle.
arxiv +1 more source