Results 101 to 110 of about 9,774,757 (278)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A Proposal for Key Sustainability Credit Assessment Criteria to Update and Develop International Ranking Systems for Green Buildings [PDF]

open access: yesصفه, 2017
As they are mainly focused on the environmental side of sustainability, a concentration on green certificates’ credit systems risks neglecting the bigger picture.
Maryam Mollazadeh Yazdani
doaj  

High concentration insulin

open access: yesIndian Journal of Endocrinology and Metabolism, 2018
This communication reviews available high concentration insulins and their basic as well as clinical pharmacology. It classifies all high concentration insulins, and describes their pharmacokinetic and pharmacodynamic properties. The article discusses the utility of high concentrations insulins, lists indications for these preparations, highlights ...
openaire   +3 more sources

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Heterogeneous ensemble learning: modified ConvNextTiny for detecting molecular expression of breast cancer on standard biomarkers

open access: yesFrontiers in Computer Science
Breast cancer is the highest-ranking type of cancer, with 2.3 million new cases diagnosed each year. Immunohistochemistry (IHC) is the gold standard “examination” for determining the expression of cancer malignancies in patients with the ultimate goal of
Indo Intan   +6 more
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Trends and Hot Spots of Macrophages Linked to Metabolic Syndrome: A Comprehensive Bibliometric and Visualization Analysis (2014–2024)

open access: yesMediators of Inflammation
Conclusion: This study systematically evaluates the research landscape, priorities, and emerging trends of macrophages associated with MetS over the last decade, providing an overview of the field and valuable insights for researchers.
Yuan Zhang   +4 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

The Concentration’s Influence of the Abrasive Granules Particles on the Vibratory Finishing Optimization [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2018
The already initiated studies are based on size and forms of abrasive grains, but few studies have addressed the influence on the concentration of abrasive grains.
Youcef Rouabhi, Azzedine Lounis
doaj  

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