Results 81 to 90 of about 9,905,190 (295)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Giant cold satellites from low-concentration haloes
The dwarf satellite galaxies of the Milky Way Crater II and Antlia II have uncommonly low dynamical mass densities, due to their large size and low velocity dispersion.
Amorisco, Nicola C.
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Concentration fluctuations in atmospheric dispersion [PDF]
This report summarizes work done at Brunel University under Agreement No.2066/62 from 15 July 1986 to 14 July 1989. The title of the project was Concentration Fluctuations in Atmospheric Dispersion. The report has three principal components. These are:
Chatwin, PC, Hajian, NT
core
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Requirements for two-source entanglement concentration
Entanglement enhancement is a key task for quantum technologies. This operation performed on states produced by parametric down-conversion sources has been the object of several recent experimental investigations.
Barbieri, Marco +7 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Upregulation of nephrin expression occurs at the early stage of nephropathy and decrease in the period 6 months on hyperglycaemic condition. Nephrin is associated with the initial stage of the loss of the permeability barrier in diabetic nephropathy ...
Rudy Salam, Diana Lyrawati, Nur Samsu
doaj +1 more source
Predicting malting barley protein concentration [PDF]
The preferred grain protein concentration (CP) of malting barley is 10.5-11.0%, but 9.5-11.5% is acceptable. It is a challenge for farmers to achieve this target with crops grown in heterogeneous fields and exposed to fluctuating weather conditions ...
Pettersson, C.G.
core
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source

