Results 81 to 90 of about 9,905,190 (295)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Giant cold satellites from low-concentration haloes

open access: yes, 2019
The dwarf satellite galaxies of the Milky Way Crater II and Antlia II have uncommonly low dynamical mass densities, due to their large size and low velocity dispersion.
Amorisco, Nicola C.
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Concentration fluctuations in atmospheric dispersion [PDF]

open access: yes, 1990
This report summarizes work done at Brunel University under Agreement No.2066/62 from 15 July 1986 to 14 July 1989. The title of the project was Concentration Fluctuations in Atmospheric Dispersion. The report has three principal components. These are:
Chatwin, PC, Hajian, NT
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Requirements for two-source entanglement concentration

open access: yes, 2013
Entanglement enhancement is a key task for quantum technologies. This operation performed on states produced by parametric down-conversion sources has been the object of several recent experimental investigations.
Barbieri, Marco   +7 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Role of Antibody Anti-AGE in the Expression of Nephrin and RAGE on Primary Glomerulus Cell Exposed with AGE

open access: yesJournal of Tropical Life Science, 2017
Upregulation of nephrin expression occurs at the early stage of nephropathy and decrease in the period 6 months on hyperglycaemic condition. Nephrin is associated with the initial stage of the loss of the permeability barrier in diabetic nephropathy ...
Rudy Salam, Diana Lyrawati, Nur Samsu
doaj   +1 more source

Predicting malting barley protein concentration [PDF]

open access: yes, 2007
The preferred grain protein concentration (CP) of malting barley is 10.5-11.0%, but 9.5-11.5% is acceptable. It is a challenge for farmers to achieve this target with crops grown in heterogeneous fields and exposed to fluctuating weather conditions ...
Pettersson, C.G.
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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