Results 101 to 110 of about 6,024,152 (295)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Trends and Hot Spots of Macrophages Linked to Metabolic Syndrome: A Comprehensive Bibliometric and Visualization Analysis (2014–2024)

Mediators of Inflammation
Conclusion: This study systematically evaluates the research landscape, priorities, and emerging trends of macrophages associated with MetS over the last decade, providing an overview of the field and valuable insights for researchers.
Yuan Zhang, Qiwang He, Xiaoqian Cong, Huazhou Qiu, Chuan Hua   +4 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Concentration Gradients [PDF]

, 2010
This RLO describes the concept of concentration gradients in biological systems through analogy with gradients found in everyday life, and outlines passive and active transport across cell membranes.
Fred Riley
core  

The Concentration’s Influence of the Abrasive Granules Particles on the Vibratory Finishing Optimization [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2018
The already initiated studies are based on size and forms of abrasive grains, but few studies have addressed the influence on the concentration of abrasive grains.
Youcef Rouabhi, Azzedine Lounis
doaj  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Flume study on the concentration of ilmenite in fine-grained sand and implications concerning uranium mineralization in the Beaufort Group [PDF]

, 1990
To establish the basic hydrodynamic controls on the distribution and concentration of heavy minerals under different flow regime conditions, three flume runs were conducted using natural sand similar to that of the Beaufort sandstones.
Le Roux J.P.
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Koinsidens Insulinoma dan Sindrom Cushing: Laporan Kasus

Jurnal Ilmu Kesehatan Indonesia
Latar belakang: Insulinoma adalah tumor neuroendokrin langka yang menyebabkan pelepasan insulin yang tidak tepat. Penggunaan kortikosteroid kronis adalah penyebab paling umum dari Sindrom Cushing.
Ida Bagus Aditya Nugraha, Wira Gotera
doaj   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source