Results 71 to 80 of about 4,255,573 (219)

Behavioral Determinants of Childhood Obesity in the United States: An Exploratory Study

Journal of Obesity
Childhood obesity is a complex and multifactorial phenomenon. Understanding these factors is crucial in developing effective interventions to prevent and treat childhood obesity.
Soumitra Palit, Tahia Sufyani, Joseph N. Inungu, Chin-I. Cheng, Emmanuel Nartey   +4 more
doaj   +1 more source

Produção de crisântemo (Dendranthema grandiflora Tzvelev.) 'Snowdon' em vaso I: doses e freqüências de aplicação de daminozide Production of chrysanthemum (Dendranthema grandiflora Tzvelev.), cv. 'Snowdon', in pots I: daminozide's concentrations and times of application

Ciência Rural, 2003
O trabalho teve como objetivo avaliar a resposta de crisântemo através da análise de parâmetros fenométricos, ao redutor de crescimento Daminozide, pulverizado na cultivar de crisântemo de corte "Snowdon", cultivada em vaso. O estudo foi formado por dois
Jucelma de Cássia Câmara Tolotti, Rogério Antônio Bellé, Leandro Mainardi   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

A Proposal for Key Sustainability Credit Assessment Criteria to Update and Develop International Ranking Systems for Green Buildings [PDF]

صفه, 2017
As they are mainly focused on the environmental side of sustainability, a concentration on green certificates’ credit systems risks neglecting the bigger picture.
Maryam Mollazadeh Yazdani
doaj  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Microbial Communities Vary by Body Region but Remain Consistent Across Color Morphs in the Solitary Ascidian Rhopalaea abdominalis

International Journal of Microbiology
Ascidians are filter-feeding marine invertebrates that display inter- and intraspecific color variation and host diverse microbiomes. Although color variation has been used as an indicator of speciation and correlated with distinct microbiome structure ...
Brenna Hutchings, Susanna López-Legentil, Lauren M. Stefaniak, Marie L. Nydam, Patrick M. Erwin   +4 more
doaj   +1 more source

Heterogeneous ensemble learning: modified ConvNextTiny for detecting molecular expression of breast cancer on standard biomarkers

Frontiers in Computer Science
Breast cancer is the highest-ranking type of cancer, with 2.3 million new cases diagnosed each year. Immunohistochemistry (IHC) is the gold standard “examination” for determining the expression of cancer malignancies in patients with the ultimate goal of
Indo Intan, Andrea Stevens Karnyoto, Sitti Harlina, Berti Julian Nelwan, Devin Setiawan, Amalia Yamin, Ririn Endah Puspitasari   +6 more
doaj   +1 more source