Results 221 to 230 of about 9,905,190 (295)

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Emergency decontamination of leaked unsymmetrical dimethylhydrazine with carboxyl-rich graphene oxide: performance and mechanism. [PDF]

RSC Adv
Hou Z, Huang Y, Jia Y, Du L, Zheng D, Li W, Ling X, Shen K, Jin G.   +8 more
europepmc   +1 more source

Impact of <i>Mycoplasma hominis</i> on Sperm Quality Among Infertile Men: A Systematic Review and Meta-Analysis. [PDF]

Health Sci Rep
Boujemaa S, Suri GS, Kaur G.
europepmc   +1 more source

The potential clinical significance of immunomodulation of immune and inflammatory responses involving selected adipokines in patients with ovarian cancer - preliminary studies. [PDF]

Front Oncol
Stępień S, Morawiec ML, Smycz-Kubańska M, Witek A, Mielczarek-Palacz A.   +4 more
europepmc   +1 more source