Results 91 to 100 of about 4,717,932 (275)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

A new neutron study of the short range order inversion in Fe$_{1-x}$Cr$_x$

, 2010
We have performed new neutron diffuse scattering measurements in Fe$_{1-x}$Cr$_x$ solid solutions, in a concentration range 0$
G. Parette, I. Mirebeau, J. Friedel, M. A. Krivoglaz, N. P. Filipova   +4 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Blood Concentration Changes in Influenza [PDF]

Proceedings of the National Academy of Sciences, 1920
F P, Underhill, M, Ringer
openaire   +3 more sources

Encoding of Slowly Fluctuating Concentration Changes by Cockroach Olfactory Receptor Neurons Is Invariant to Air Flow Velocity

Frontiers in Physiology, 2019
The ON and OFF olfactory receptor neurons (ORNs) on the cockroach antenna display a high sensitivity for the rate at which odorant concentration changes.
Maria Hellwig, Alexander Martzok, Harald Tichy   +2 more
doaj   +1 more source

TECHNOLOGICAL CHANGE IN THE U.S. BEEF AND PORK SECTORS: IMPACTS ON FARM-WHOLESALE MARKETING MARGINS AND LIVESTOCK PRICES [PDF]

Real livestock prices and farm-wholesale marketing margins have steadily declined over the past 20 years. Many studies have examined the effects of increasing packer concentration on these declines. However, most have generally failed to account directly
Brester, Gary W., Marsh, John M.
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

On the Refractive Index of Ageing Dispersions of Laponite

, 2008
Aqueous dispersion of Laponite at low ionic concentration is of interest since it undergoes structural evolution with respect to time, which is usually termed as ageing.
Abou, Andreola, Bonn, Cipelletti, de Gennes, Fielding, Goldstein, Huang, Joshi, Joshi, Joshi, K. Muralidhar, Lagaly, Lorentz, Mossa, Mourchid, Mourchid, N.V.N. Ravi Kumar, Niskanen, Ramsay, Ruzicka, Ruzicka, Schiebener, Schosseler, Tan, Tanaka, Tanaka, Tanio, Van Olphen, Wu, Yogesh M. Joshi   +30 more
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source