Results 101 to 110 of about 4,717,932 (275)
Background: In general, patients with osteoarthritis require long live treatments, especially anti-infammatory drugs. Non steroidal anti infammatory drugs are mostly follow by some side effects such as dyspepsia and gastrointestinal bleeding.
Nyoman Kertia +3 more
doaj +1 more source
RNA-based cooperative protein labeling that permits direct monitoring of the intracellular concentration change of an endogenous protein. [PDF]
Pe KBA +6 more
europepmc +1 more source
Changes in Ochratoxin A Concentration during Winemaking
The effects of common winemaking procedures on ochratoxin A (OTA) concentrations in the Portuguese wine Vinho Verde were studied. Natural contamination of grapes was not observed, so grapes for vinification were inoculated with Aspergillus carbonarius. Ochratoxin A concentration in these grapes ranged from 0.43 to 7.48 μg/kg.
Fernandes, Anabela +4 more
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
CHANGE IN THE CONCENTRATION OF BUSINESS ACTIVITIES IN THE REGIONS OF BULGARIA
The aim of the article is to bind the changes concerning business activity, foreign direct investment and internal migration of the population. The research period is 15 years.
P. Atanasova
doaj +1 more source
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The emergence of large shareholders in mass privatized firms: Evidence from Poland and the Czech Republic [PDF]
Mass privatization offers a particularly suitable framework to study the change in ownership concentration as the extent of change is unusual for a stable market economy.
Iraj Hashi, Irena Grosfeld
core +3 more sources
Pollutant Photodegradation Affected by Evaporative Water Concentration in a Climate Change Scenario
Evaporative water concentration takes place in arid or semi-arid environments when stationary water bodies, such as lakes or ponds, prevalently lose water by evaporation, which prevails over outflow or seepage into aquifers.
Arianna Rosso, Davide Vione
doaj +1 more source

