Results 61 to 70 of about 451,734 (249)

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li, Dong‐Lin Liang, Li‐Ping Gao, Wei‐Wei Zhang, Wei Zhou, A. Ruhan, Bing Xu, Run‐Dong Cao, Kang Xiao, Cao Chen, Qi Shi, Xiao‐Ping Dong   +11 more
wiley   +1 more source

Anion Concentration Distribution and Gravity Analysis of Tourism Resources in Qinhuangdao Liujiang National Nature Reserve, National Geological Park

Sustainable Development, 2017
本文介绍了秦皇岛柳江盆地的整体状况及旅游资源，并采用城市引力模型，从实际数据角度分析了秦皇岛柳江盆地的潜在游客来源，同时根据实际情况对柳江盆地旅游业的发展提出了一定的建议。在分析模型数据的基础上进一步说明柳江盆地旅游资源的发展潜力，为人居环境提出一定的建设性意见。 The paper introduces the overall situation of Qinhuangdao Liujiang river basin and the tourism resources, and the urban gravity model is adopted.
openaire   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias, Federica Avantaggiato, Gianni Pezzoli, Andrea Canessa   +3 more
wiley   +1 more source

High-Spatial-Resolution Helium Detection and Its Implications for Helium Accumulation Mechanisms

Applied Sciences
Helium is a scarce strategic resource. Currently, all economically valuable helium resources are found in natural gas reservoirs. Owing to helium’s different formation and migration processes compared to natural gas’s, the traditional method of ...
Chao Lu, Bang Wang, Di Zhu, Quanyou Liu, Xuhang Zhang, Huaiyu He   +5 more
doaj   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Removal of Tetracycline from Synthetic Solution by Natural LECA

Muhandisī-i Bihdāsht-i Muḥīṭ, 2014
Background: Antibiotic in environment can be accumulated in soil and sediment and then adversely affect the ecosystem function as well as decrease the natural degradation rate of pollutants by producing a antibiotic-resistant microorganisms.
Mohammad Noori Sepehr, Samira Mohebi, Shiva Abdlollahi Vahed, Mansur Zarrabi   +3 more
doaj  

CO2 concentration testing as a quick estimate of natural ventilation effectiveness in primary healthcare: experience in war-affected, resource-limited settings

Infection Prevention in Practice
Ventilation remains an important component of infection prevention and control programmes. Natural ventilation, as the most affordable measure to control airborne transmission of pathogens, is a crucial area of focus. However, applying natural ventilation encounters challenges in routine practice, especially in emergencies.
Dolynska, M., Aleksandrin, A., Vlasenko, O., Gorischak, S., Dolynskyi, G., Vodianyk, A.   +5 more
openaire   +2 more sources

Endothelial Cell Proteins as Biomarkers in Susac Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin, Yue Andy Qi, Ying Hao, Catherine DeMarino, Samuel Darko, Irene Cortese, Daniel S. Reich, María I. Gaitán, Steven Jacobson, Bridgett J. Billioux, Bryan Smith, Avindra Nath   +11 more
wiley   +1 more source

Optimization of Nano-Tangeretin Recrystallization via Natural Surfactants in the Antisolvent Precipitation Process: Physicochemical Characterization and Antioxidant Activity

Nanomaterials
In this study, an improved method combining natural surfactants with a solvent–antisolvent precipitation technique was developed to prepare highly effective nano-sized tangeretin particles.
Yan Huang, Wenxuan Huang, Xiaonan Zhang, Zhiwei Liu   +3 more
doaj   +1 more source

Combined Process‐ and Phase‐Field‐Simulation to Predict the Microstructure of Single‐Crystal Ni‐Based Superalloys

Advanced Engineering Materials, EarlyView.
A combined finite element and phase‐field approach predicts the evolution of microstructure during the directional solidification of Ni‐based superalloys. The model reveals how withdrawal rate, temperature gradient, and wall thickness control the dendrite spacing, highlighting the strong effect of surface regions in thin sections where dendrite growth ...
Sean Böhm, André B. Baldissera, Rainer Völkl, Uwe Glatzel   +3 more
wiley   +1 more source