Results 261 to 270 of about 9,618,149 (357)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Tensions regarding inclusion meanings from stakeholders' perspectives: A qualitative study. [PDF]

PLoS One
Solis-Grant MJ, Bretti-López MJ, Sepúlveda-Carrasco C, Pérez-Villalobos C, Sepúlveda-Witt T, Reinoso-González E, Hernández-Quidel JF.   +6 more
europepmc   +1 more source

Quasi-Contracts: Concept of Benefit

, 1948
G. A. Rinker
openalex   +2 more sources

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

The concept of medial pivot design from primary to revision total knee arthroplasty: a technical note. [PDF]

Arch Orthop Trauma Surg
Sadoghi P.
europepmc   +1 more source

The Importance and Concepts of the Feedback Control

, 1953
Yasundo Takahashi
openalex   +2 more sources

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Safety huddle in healthcare settings: a concept analysis. [PDF]

BMC Health Serv Res
Ghoul I, Abdullah A, Awwad F, Dardas LA.
europepmc   +1 more source

Mapping Hsp104 interactions using cross‐linking mass spectrometry

FEBS Open Bio, EarlyView.
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal, Karolina Michalska, Andrzej Joachimiak, Lukasz A. Joachimiak   +3 more
wiley   +1 more source

Tai Chi training can improve postural control

Revista de Artes Marciales Asiáticas, 2016
Orlando Fernandes, Fábio Basilio
doaj   +1 more source