Results 41 to 50 of about 3,600,183 (247)

Trans Utopianism and the Utopia of Transness in Leslie Feinberg’s Stone Butch Blues [PDF]

open access: yes, 2019
Theory can sometimes only find its synthesis in fiction. The debate within queer theory between the anti-social and the utopian has been dominating discourse for nearly a decade.

core   +1 more source

Vol. 4 No. 2 Summer 2013 [PDF]

open access: yes, 2013
Tania de St Croix; liam Kan; Mike newman; Jo Northedge; Mae Shaw; Jo McFarlane; Ross ...
Journal, Concept
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Semen Proile of Infertile Males Attending Private Infertility Clinic of Metropolitan City of Pakistan

open access: yesJournal of the Dow University of Health Sciences, 2018
Objective: To determine the semen profile of male partner of infertile couples coming for treatment of infertility in a private infertility clinic of metropolitan city of Pakistan.
Qurat ul Aman Siddiqui   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

On Concept of Concept

open access: yesWorld Journal of Education and Humanities, 2019
It gives Prof. Zhiyong Dong’s own definition of the concept of concept.
openaire   +2 more sources

Biofeedback and Anxiety Disorders: A Critical Review of EMG, EEG, and HRV Feedback [PDF]

open access: yes, 2015
Anxiety disorders are characterized by ongoing and situationally disproportionate fear and anxiety, and the associated significant distress and impairment of normal functioning (American Psychiatric Association, 2013).

core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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