Results 51 to 60 of about 4,198,885 (319)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Celebrating 25 Years of Concept: The First Issue, Autum 1990

, 2015
This is the first every copy of concept, autum 1990.
Editorial Board, Concept
core  

The economic and health impact of substandard uterotonic use for prevention of postpartum hemorrhage in three Sub-Saharan African countries: a comparative analysis

Health Research Policy and Systems
Background Uterotonics are essential in reducing the risk of postpartum haemorrhage (PPH) and saving mothers’ lives. However, numerous quality-testing studies have found that uterotonics in many low- and middle-income countries are substandard.
Petra Procter, Sara Rushwan, Yi-Fang Ashley Lee, Colleen R. Higgins, A. Metin Gülmezoglu, Lester Chinery, Sachiko Ozawa   +6 more
doaj   +1 more source

Active Packaging Films from PBAT/PLA with Rosmarinus officinalis L. Extract: Antioxidant, UV-Shielding, and Compostable Properties

Molecules
With the growing demand for eco-friendly food packaging, poly(butylene adipate-co-terephthalate) (PBAT)/polylactic acid (PLA) composite films have emerged as promising biodegradable alternatives, but their inherent limitations (e.g., poor antioxidant ...
Xiaoyan He, Lisheng Tang, Ran Huang
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

CONCEPT EDISI JANUARI S/D OKTOBER 2011

, 2015
Past Pressent ...
CONCEPT
core  

Environmental predictors of distribution of herbaceous endemic species from lateritic rock outcrops of the Western Ghats and Konkan region, India

Discover Plants
Endemism serves as an ecological metric and indicator, informing conservation planning worldwide. Within this context, the Western Ghats emerge as a pivotal biogeographical region, particularly renowned for its rich array of endemic species.
Rutuja R. Kolte, Girish M. Kulkarni, Rohan H. Shetti, Rahul D. Prabhukhanolkar, Malapati K. Janarthanam, Aboli G. Kulkarni   +5 more
doaj   +1 more source

Suspensão e neutralidade evidencial

Perspectiva Filosófica, 2020
Neste artigo discuto uma tese sobre a racionalidade da suspensão de juízo de que suspensão de juízo racional requer neutralidade evidencial. Após traçar alguns pontos sobre as noções probabilísticas de neutralidade e suporte evidencial, aponto uma ...
Luis Rosa
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source