Results 51 to 60 of about 14,451,026 (391)
‘My favourite things to do’ and ‘my favourite people’: Exploring salient aspects of children’s self-concept [PDF]
This study explores the potential of the ‘draw-and-write’ method for inviting children to communicate salient aspects of their self-concept. Irish primary school children aged 10–13 years drew and wrote about their favourite people and things to do ...
Damon, W.+18 more
core +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source
The aerospace developments concept [PDF]
The viability of using airships for the transport of natural gas, and the initial design of such a system, the airship and its associated subsystems together with a continuing economic analysis of the project were investigated.
Wood, J. E. R.
core +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
The selection of rootstocks is one of the first and most important stages in the establishment of grape plantations under grafted conditions, which determines the productivity of rootstock-scion combinations and the further chain of design solutions ...
А. А. Averianov+2 more
doaj +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Objective: To determine the semen profile of male partner of infertile couples coming for treatment of infertility in a private infertility clinic of metropolitan city of Pakistan.
Qurat ul Aman Siddiqui+3 more
doaj +1 more source
Loneliness: A Concept Analysis [PDF]
TOPIC. Loneliness is a universal human experience recognized since the dawn of time, yet it is unique for every individual. Loneliness can lead to both depression and low self‐esteem. PURPOSE. This article explicates the concept of loneliness through the
Bekhet, Abir K.+1 more
core +1 more source
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
A stepwise emergence of evolution in the RNA world
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source