Results 81 to 90 of about 1,988,205 (269)

Wide alar base: Minimally invasive intraoral interalar suture for enhancing facial aesthetics

Advances in Oral and Maxillofacial Surgery, 2023
Stella Aparecida de Andrade Pinto, José Hyczy Fonseca Junior, Renata Sari Precetti, Danilo Siqueira Pino, Francisco José de Nadai Dias   +4 more
doaj   +1 more source

The Concept of Truth

Synthese, 2001
On the basis of elementary thinking about language functioning, a solution of truth paradoxes is given and a corresponding semantics of a truth predicate is founded. It is shown that it is precisely the two-valued description of the maximal intrinsic fixed point of the strong Kleene three-valued semantics.
openaire   +4 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Type-2 immunity associated with type-1 related skin inflammatory diseases: friend or foe?

Frontiers in Immunology
Chronic inflammatory skin diseases are multifactorial diseases that combine genetic predisposition, environmental triggers, and metabolic disturbances associated with abnormal immune responses.
Laure Migayron, Laure Migayron, Sylvie Bordes, Brigitte Closs, Julien Seneschal, Julien Seneschal, Katia Boniface   +6 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

251 The use of small molecule inhibitors to target novel pathways in exhausted T cells for immuno-oncology therapeutic intervention

Journal for ImmunoTherapy of Cancer, 2021
Preeti Singh, Francis Acklam, Joanne Hay, Darryl Turner, Mark Barbour, Courtney Grant, Hayley Gooding, Justyna Rzepecka, Rhoanne McPherson   +8 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Tapping into tradition: a multi-method approach for reviving Tanka for climate-resilient water management in Ahmedabad

Built Heritage
Ahmedabad, a city that is layered with centuries of traditional knowledge systems, showcases a unique adaptation to socio-environmental and economic challenges.
Piyush Pandya, Maniti Desai, Debalina Ghosh   +2 more
doaj   +1 more source