Results 101 to 110 of about 3,595,676 (296)

Fast Learning and Testing for Imbalanced Multi-Class Changes in Streaming Data by Dynamic Multi-Stratum Network

open access: yesIEEE Access, 2017
Although several efficient learning methods have recently been proposed to handle class drift situations, issues remain in various streaming data applications that possibly deteriorate classification accuracy. Three important issues were considered, that
Mongkhon Thakong   +3 more
doaj   +1 more source

Are Random Drift and Natural Selection Conceptually Distinct? [PDF]

open access: yes, 2001
The latter half of the twentieth century has been marked by debates in evolutionary biology over the relative significance of natural selection and random drift: the so-called neutralist/selectionist debates.
Millstein, Roberta L.
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

German Regulation – Drift Modelling

open access: yes, 2004
The application of plant protection products is associated with the unavoidable occurrence of direct drift. The volume of transported and deposited drops is influenced by prevailing technical, technological, and meteorological conditions.
Moll, Eckhard   +3 more
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Dynamic domain analysis for predicting concept drift in engineering AI-enabled software

open access: yesJournal of Data and Information Science
This research addresses the challenge of concept drift in AI-enabled software, particularly within autonomous vehicle systems where concept drift in object recognition (like pedestrian detection) can lead to misclassifications and safety risks.
Shahzad Murtuza   +4 more
doaj   +1 more source

Concept Drift Detection Based on Typicality and Eccentricity

open access: yesIEEE Access
Many applications and fields produce a vast quantity of time-relevant or continuously changing data which may represent new phenomena. This data stream behavior is known as Concept Drift. The need to efficiently and accurately process online data streams
Yuri Thomas P. Nunes   +1 more
doaj   +1 more source

Vol. 4 No. 2 Summer 2013 [PDF]

open access: yes, 2013
Tania de St Croix; liam Kan; Mike newman; Jo Northedge; Mae Shaw; Jo McFarlane; Ross ...
Journal, Concept
core  

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