Results 121 to 130 of about 2,843,609 (294)
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Low Thrust Augmented Spacecraft Formation-Flying [PDF]
, 2015 Ballistic spacecraft formation-flying with zero thrust has great utility, but it is limited to a comparatively small set of relative trajectories.
Arnot, Callum S., McInnes, Colin R.
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Urban morphology and transformation the pattern of housing in the historical cities of Iran [PDF]
, 2018 Regardless of the historical and cultural collapse of today's contemporary architecture that arose in the aftermath of the advent of modernity, if we look at the process of the emergence of architecture before this era, we see that most architectural ...
NAHAS FARMANIYEH, Farzaneh +1 more
core
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
, 1990 This thesis provides a conceptual and empirical analysis of implicit concept formation. A review of concept formation studies highlights the need for improving existing methodology in establish- ing the claim for implicit concept formation. Eight experiments are reported that address this aim.
Dienes, Z, Dienes, Zoltan
openaire +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Psicologia: Reflexão e Crítica, 2008 This study assessed the performance of 20 persons with autism in an identity matching-to-sample task, using two procedures with different stimuli arrangements and different response requirements.
Camila Graciella Santos Gomes +1 more
doaj
Formação de conceitos em crianças cegas: questões teóricas e implicações educacionais
Psicologia: Teoria e PesquisaA formação de conceitos depende da linguagem e do pensamento, que integram informações sensoriais. Postula-se que mudanças no sujeito que conhece e nos objetos e eventos a serem conhecidos sugerem modelos flexíveis de ensino de conceitos.
Cecilia Guarnieri Batista
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source