Results 101 to 110 of about 7,783,300 (285)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Reading Death and Sacrifice in the Berlin Völkischer Beobachter, February 1942 – March 1943 [PDF]
, 2010 ...
core +1 more source
Integrated Cognitive Architecture for Robot Learning of Action and Language
Frontiers in Robotics and AI, 2019 The manner in which humans learn, plan, and decide actions is a very compelling subject. Moreover, the mechanism behind high-level cognitive functions, such as action planning, language understanding, and logical thinking, has not yet been fully ...
Kazuki Miyazawa +5 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Inequality in the Caribbean: A Case Study of Hispaniola [PDF]
, 2015 I examine the effects democratization, institution building, and colonization have on the political and economic stability and inequality in the Caribbean; specifically, I argue that each of these variables contributes to the political and economic ...
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Concept formation is predominantly analyzed in classrooms and laboratory experiments, meaning the collective formation of culturally novel concepts in practical activities 'in the wild' has largely been neglected. However, understanding and influencing the complexity and contradictions of the present world demands powerful concepts that can make a ...
openaire +2 more sources
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Incivility in Nursing Education: A Concept Analysis
Iranian Journal of Nursing and Midwifery ResearchBackground: Incivility in nursing education is a complex concept that is not exactly defined in nursing. The purpose of this study was to clarify the concept of incivility in nursing education in the Iranian cultural context.
Zahra Abedini +4 more
doaj +1 more source