Results 81 to 90 of about 2,843,609 (294)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Cuidado transpessoal em enfermagem: uma análise pautada em modelo conceitual

Revista da Escola de Enfermagem da USP
Estudo teórico que objetivou analisar os atributos, antecedentes e consequências do conceito cuidado transpessoal, mediante utilização do Modelo de Análise de Conceito. Para isso, elencaram-se livros publicados pela teórica Jean Watson, em português e em
Luciane Favero, Lorita Marlena Freitag Pagliuca, Maria Ribeiro Lacerda   +2 more
doaj  

Historical evolution of the concept environment proposed in the Roy adaptation model Evolución histórica del concepto entorno propuesto en el modelo de la adaptación de Roy Evolução histórica do conceito ambiente proposto no modelo da adaptação de Roy

Revista Latino-Americana de Enfermagem, 2006
The concern for the development of concepts becomes even more important when we report to its use in Nursing theories, in which some concepts are considered central, such as person, environment, health and nursing.
Marcos Venícios de Oliveira Lopes, Lorita Marlena Freitag Pagliuca, Thelma Leite de Araujo   +2 more
doaj   +1 more source

The structure and formation of natural categories [PDF]

Categorization and concept formation are critical activities of intelligence. These processes and the conceptual structures that support them raise important issues at the interface of cognitive psychology and artificial intelligence.
Fisher, Douglas, Langley, Pat
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Structure learning enhances concept formation in synthetic Active Inference agents. [PDF]

PLoS One, 2022
Neacsu V, Mirza MB, Adams RA, Friston KJ.   +3 more
europepmc   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Influence of language on perception and concept formation in a brain-constrained deep neural network model. [PDF]

Philos Trans R Soc Lond B Biol Sci, 2023
Henningsen-Schomers MR, Garagnani M, Pulvermüller F.   +2 more
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Kick-starting concept formation with intrinsically motivated learning: the grounding by competence acquisition hypothesis. [PDF]

Philos Trans R Soc Lond B Biol Sci, 2023
Mannella F, Tummolini L.
europepmc   +1 more source