Results 161 to 170 of about 11,719,816 (381)
Prime number logarithmic geometry on the plane
, 2002 We found a regularity of the behavior of primes that allows to represent both prime and natural numbers as infinite matrices with a common formation rule of their rows.
Alexandrov, Lubomir
core +2 more sources
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Desenvolvimento de conceitos: o paradigma das descobertas
Psicologia Escolar e EducacionalKeil investigou se a descoberta de essências internas ou princípios causais subjacentes alterariam as categorizações de crianças sobre conceitos de espécies naturais e artefatos. Esse trabalho replica parte do experimento de Keil (1989), buscando validar
José Fernando Bitencourt Lomônaco +5 more
doaj
The Role of Trust in Costly Network Formation [PDF]
We consider game theoretic models of social network formation.In this paper we limit our investigation to game theoretic models of network formation that are based on individual actions only.Our approach is based on three simple and realistic principles:
Gilles, R.P., Sarangi, S.
core +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Coalition formation in simple games: The semistrict core [PDF]
We consider the class of proper monotonic simple games and study coalition formation when an exogenous share vector and a solution concept are combined to guide the distribution of coalitional worth.
Claus-Jochen Haake, Dinko Dimitrov
core
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source