Results 31 to 40 of about 544,256 (319)

Desenvolvimento de conceitos: o paradigma das transformações

Psicologia: Teoria e Pesquisa
Keil (1989) investigou se artefatos e espécies naturais permaneciam membros das mesmas categorias após transformações mudando seus aspectos característicos mais salientes. Este trabalho replica um de seus experimentos, objetivando comprovar a validade de
José Fernando Bitencourt Lomônaco, Fräulein Vidigal de Paula, Cláudia Berlin de Mello, Fabiane de Amorim Almeida   +3 more
doaj   +1 more source

Speciation Through the Lens of Population Dynamics: A Theoretical Primer on How Small and Large Populations Diverge

Population Ecology, EarlyView.
Population size and dynamics fundamentally shape speciation by influencing genetic drift, founder events, and adaptive potential. Small populations may speciate rapidly due to stronger drift, whereas large populations harbor more genetic diversity, which can alter divergence trajectories. We highlight theoretical models that incorporate population size
Ryo Yamaguchi, Hidaka Kubo, Tokuya Ogawa, Hayate Omura   +3 more
wiley   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

Social support and social network in family nursing: reviewing concepts Red y apoyo social en enfermería familiar: revisión de conceptos Apoio e rede social em enfermagem familiar: revendo conceitos

Revista Latino-Americana de Enfermagem, 2008
Social support and social network concepts are resources applicable to Family Nursing, as they are aimed at improving families' quality of life, and also at promoting, strengthening and maintaining their well-being.
Iara Cristina da Silva Pedro, Semiramis Melani Melo Rocha, Lucila Castanheira Nascimento   +2 more
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Beyond the Failure of Direct-Matching in Keyword Evaluation: A Sketch of a Graph Based Solution

Frontiers in Artificial Intelligence, 2022
The starting point of this paper is the observation that methods based on the direct match of keywords are inadequate because they do not consider the cognitive ability of concept formation and abstraction.
Max Kölbl, Yuki Kyogoku, J. Nathanael Philipp, Michael Richter, Clements Rietdorf, Tariq Yousef   +5 more
doaj   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Explanatory Models and Medication Adherence in Patients with Depression in South India [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Conceptualization of depression may have bearing on treatment seeking. It may affect adherence behaviour of the patients. Aim: To find out the explanatory models and their relationship with socio-demographic variables and medication ...
Dushad Ram, Adarsh Lakkur Siddappa, Rajesh Raman, Basavana Gowdappa Hattur   +3 more
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source