Results 41 to 50 of about 7,783,300 (285)

“And a door opens”: reflections on conceptual and identity issues on clinical reasoning in occupational therapy

Cadernos Brasileiros de Terapia Ocupacional, 2019
Introduction: Placing practice in words is an arduous task for occupational therapists by considering the narrative aspects of practice in the complex and multifaceted relationships between human beings and society.
Taís Quevedo Marcolino, Jéssica Cristina Von Poellnitz, Carla Regina Silva, Cecília Cruz Villares, Aline Maria de Medeiros Rodrigues Reali   +4 more
doaj  

Explanatory Models and Medication Adherence in Patients with Depression in South India [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Conceptualization of depression may have bearing on treatment seeking. It may affect adherence behaviour of the patients. Aim: To find out the explanatory models and their relationship with socio-demographic variables and medication ...
Dushad Ram, Adarsh Lakkur Siddappa, Rajesh Raman, Basavana Gowdappa Hattur   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Desenvolvimento de conceitos: o paradigma das transformações

Psicologia: Teoria e Pesquisa
Keil (1989) investigou se artefatos e espécies naturais permaneciam membros das mesmas categorias após transformações mudando seus aspectos característicos mais salientes. Este trabalho replica um de seus experimentos, objetivando comprovar a validade de
José Fernando Bitencourt Lomônaco, Fräulein Vidigal de Paula, Cláudia Berlin de Mello, Fabiane de Amorim Almeida   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Vol. 4 No. 2 Summer 2013 [PDF]

, 2013
Tania de St Croix; liam Kan; Mike newman; Jo Northedge; Mae Shaw; Jo McFarlane; Ross ...
Journal, Concept
core  

Social support and social network in family nursing: reviewing concepts Red y apoyo social en enfermería familiar: revisión de conceptos Apoio e rede social em enfermagem familiar: revendo conceitos

Revista Latino-Americana de Enfermagem, 2008
Social support and social network concepts are resources applicable to Family Nursing, as they are aimed at improving families' quality of life, and also at promoting, strengthening and maintaining their well-being.
Iara Cristina da Silva Pedro, Semiramis Melani Melo Rocha, Lucila Castanheira Nascimento   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Development and psychometric evaluation of the ethical conflict assessment instrument in nursing: A mixed-method protocol study

Journal of Education and Health Promotion
BACKGROUND: Ethical conflict among nurses has a significant impact on their health and the quality of nursing care. The lack of specific ethical and legal signs and obstacles for reporting ethical conflict in nurses has made diagnosis and the management ...
Ebrahim Falahati, Mousa Alavi, Mohsen Shahriari   +2 more
doaj   +1 more source