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Concept Journal Vol. 4 No. 3 Winter 2013 Full Issue
Concept full ...
Full Issue, Concept
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Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Celebrating 25 Years of Concept: The First Issue, Autum 1990
This is the first every copy of concept, autum 1990.
Editorial Board, Concept
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Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Bridging the gaps in patient education through aesthetic-based education: A concept analysis study
BACKGROUND: Aesthetics is a branch of philosophy that has been entered into the philosophy of education for a long time. Reviewing the concept of aesthetics in education, we can see the components that can cover a number of challenges in the field of ...
Elham Khooshab +4 more
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Beyond the Failure of Direct-Matching in Keyword Evaluation: A Sketch of a Graph Based Solution
The starting point of this paper is the observation that methods based on the direct match of keywords are inadequate because they do not consider the cognitive ability of concept formation and abstraction.
Max Kölbl +5 more
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Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Analysis of the concept of powerlessness in individuals with stroke
Objective: To identify and analyze the concept of the powerlessness in individuals with stroke, according to the NANDA-I Taxonomy. Methods. Concept analysis from online access of four databases using the descriptors: impotence; helplessness, learned ...
Renan Alves Silva +5 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source

