Results 151 to 160 of about 348,254 (301)
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
PENINGKATAN PENGUASAAN KONSEP SINTAKSIS BAHASA INDONESIA MELALUI PENERAPAN MEDIA PETA KONSEP PADA JURUSAN PENDIDIKAN BAHASA DAN SASTRA INDONESIA [PDF]
This classroom action research aims to improve the mastery of Indonesian syntactic concepts of the students of the Indonesian Language and Literature Education Study Program, the Faculty of Languages and Arts, the Yogyakarta State University ...
Sudaryanto, -
core
Peningkatan Keterampilan Mengkomunikasikan Dan Penguasaan Konsep Kesetimbangan Kimia Siswa Melalui Model Learning Cycle 5e [PDF]
, 2013 The aim of this research is to describe the effectiveness of LC 5E learning model in improving communicate skills and mastery of concepts students on the material chemical equilibrium. The population in this study were all students of class XI IPA in ...
Efkar, T. (Tasviri) +2 more
core +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Perbedaan Penguasaan Konsep Ikatan Kimia Pembelajaran Kooperatif Nht Dengan Pembelajaran Kooperatif Tps [PDF]
, 2013 The purpose of this study is whether there is any difference between the value of student’s mastery of the concept of NHT cooperative learning with TPS cooperative learning and determine the average value of student’s concept which is higher ...
Efkar, T. (Tasviri) +2 more
core +1 more source
Software Engineering Mastery: From Concept to Deployment
Software engineering is the backbone of modern technology, enabling the creation of robust, efficient, and scalable systems that drive innovation across industries. "Software Engineering Mastery: From Concept to Deployment" represents a collaborative effort by a diverse group of professionals, academics, and industry experts to provide a comprehensive ...
openaire +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source