Results 121 to 130 of about 3,076,120 (383)

La conception de l’immortalité entre Attar et André Gide [PDF]

open access: yesAnnales du Patrimoine, 2011
Peyvand Goharpey, La conception de l’immortalité entre Attar et André ...
Peyvand Goharpey
doaj  

Conceptions d’enseignants au regard de la professionnalisation des étudiants dans des programmes universitaires en santé [PDF]

open access: diamond, 2023
Marilou Bélisle   +9 more
openalex   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Beyond healthcare access: social deprivation and COVID-19 outcomes in dialysis patients in the provence-alpes-côte d’Azur region, France

open access: yesBMC Infectious Diseases
Background Socioeconomic deprivation has been consistently associated with worse COVID-19 outcomes, yet it remains unclear whether social gradients persist in populations receiving regular, highly structured, life-sustaining care.
Franck Mazoué   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Intellectual Property’s Leviathan [PDF]

open access: yes, 2014
Neoliberalism is a complex, multifaceted concept. As such, it offers many possible points of entry into my primary field of study, that of intellectual property (IP) law.
Kapczynski, Amy
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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