Results 111 to 120 of about 1,328,254 (307)
Synthese, 2001 On the basis of elementary thinking about language functioning, a solution of truth paradoxes is given and a corresponding semantics of a truth predicate is founded. It is shown that it is precisely the two-valued description of the maximal intrinsic fixed point of the strong Kleene three-valued semantics.
openaire +5 more sources
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
La participation citoyenne en conception : évolution des rôles face aux enjeux contemporains [PDF]
peer reviewedCe chapitre s’intéresse à la conception participative d’un point de vue théorique et d’un point de vue pratique, sur base de recherches menées dans le contexte de la Smart City.
Schelings, Clémentine
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Dooyeweerd's Conception of Truth: Exposition and Critique
, 2008 This paper is the long version or “director’s cut” of two essays published by the journal Philosophia Reformata under the titles “Dooyeweerd’s Conception of Truth: Exposition and Critique” and “Unfinished Business: Toward a Reformational Conception of ...
Zuidervaart, Lambert
core +1 more source
Conception of the cognitive engineering design problem [PDF]
, 1998 Cognitive design, as the design of cognitive work and cognitive tools, is predominantly a craft practice that currently depends on the experience and insight of the designer. However, the emergence of a discipline of cognitive engineering promises a more
Long, J, Dowell, J
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
BMC Infectious DiseasesBackground Socioeconomic deprivation has been consistently associated with worse COVID-19 outcomes, yet it remains unclear whether social gradients persist in populations receiving regular, highly structured, life-sustaining care.
Franck Mazoué +6 more
doaj +1 more source
The Effect of Education on the Timing of Marriage and First Conception in Pakistan. [PDF]
It is often argued that a rapid rise in educational attainment of women, an increase in the age at marriage and an increase in the age at first birth are key features of demographic transition in any country.
Gangadharan, L., Maitra, P.
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source