Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
LA CONCEPTION DU DROIT PAR MA GRAND-MERE : SENS ET NON-SENS [PDF]
Pour ma grand-mère, tout étudiant ou toute personne qui a été à la Faculté de Droit pour apprendre serait magistrat et plus précisément juge. Il a le seul rôle à jouer dans la société, celui de juger tous ceux qui commettent les actes illicites qualifiés
Didier-Pierre NDANGI BAZEBANZIA
doaj
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Longitudinal profiling of antiphospholipid antibodies reveals pre-conception levels as a key predictor of live birth in women with recurrent pregnancy loss. [PDF]
Luo PD, Li Q, Wei SQ, Zheng PS.
europepmc +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Lucía Navarro Brotons, Paremias. Estudio lingüístico contrastivo francés-español
Paola Conception Ginette Masseau
doaj +1 more source
Weight-Lowering Drugs and Natural Female Fertility-A Systematic Review and Meta-Analysis. [PDF]
Alnaimi SJ +4 more
europepmc +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Metabolic expenditure, neurodevelopment, and weight gain into early childhood after fetal growth restriction. [PDF]
Gelegen C +7 more
europepmc +1 more source

