Results 121 to 130 of about 670,588 (269)

LA CONCEPTION DU DROIT PAR MA GRAND-MERE : SENS ET NON-SENS [PDF]

open access: yesCahiers Africains des Droits de l’Homme et de la Démocratie ainsi que du Développement Durable
Pour ma grand-mère, tout étudiant ou toute personne qui a été à la Faculté de Droit pour apprendre serait magistrat et plus précisément juge. Il a le seul rôle à jouer dans la société, celui de juger tous ceux qui commettent les actes illicites qualifiés
Didier-Pierre NDANGI BAZEBANZIA
doaj  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Conception to concept or concept to conception? From being to becoming

open access: yes, 2017
Previous approaches to mathematics knowing and learning have attempted to account for the complexity of students’ individual conceptions of a mathematical concept. Those approaches primarily focused on students’ conceptual development when a mathematical concept comes into being.
openaire   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Lucía Navarro Brotons, Paremias. Estudio lingüístico contrastivo francés-español

open access: yesHermeneus
Paola Conception Ginette Masseau
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Metabolic expenditure, neurodevelopment, and weight gain into early childhood after fetal growth restriction. [PDF]

open access: yesSci Rep
Gelegen C   +7 more
europepmc   +1 more source

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