Results 231 to 240 of about 2,934,510 (334)

Evaluation of the Antimicrobial Efficacy of Sodium Hypochlorite, Ozone, Diode Laser, and Photodynamic Therapy Against Enterococcus faecalis and Streptococcus mutans: An In-Vitro Study. [PDF]

Oral Health Prev Dent
Ozkan C, Derelioglu SS, Hanci H, Ince NNA, Sengul F, Kaplan EBE, Celikel P.   +6 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Breeding seasonality of Tylopoda: Expected patterns in Old World camelids but an exceptional pattern in South American camelids. [PDF]

PLoS One
Pauli N, Roller M, Clauss M.
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Retail pharmacy clinics in Mexico: a commentary. [PDF]

Lancet Reg Health Am
Colchero MA, Barrientos-Gutiérrez T, Hernández-Ávila M.   +2 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Pregnancy outcomes in idiopathic inflammatory myopathies: a Portuguese multicentre study. [PDF]

Front Med (Lausanne)
Lopes AR, Teodósio Chícharo A, Campanilho-Marques R, Abreu C, Rodrigues SD, Santos I, Paramés F, Barreira SC, Pulido-Valente M, Pinto L, Cruz-Machado AR, Capela S.   +11 more
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

CORRECTION: Exposure to sugar rationing in first 1000 days after conception and long term cardiovascular outcomes: natural experiment study.

BMJ
europepmc   +1 more source