Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Organizing Clericals: Problems & Prospects [PDF]
, 1986 [Excerpt] One of the central goals of contemporary feminism has been the full integration of women into the workforce. While broader economic and social forces were decisive in propelling women into full-time employment, the women\u27s movement took as ...
Lynch, Roberta
core +1 more source
Does endometrial scratching increase the rate of spontaneous conception in couples with unexplained infertility and a good prognosis (Hunault > 30%)? Study protocol of the SCRaTCH-OFO trial: a randomized controlled trial [PDF]
, 2018 Bich Ngoc Bui +19 more
openalex +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Factors Affecting Conception Rates Following Artificial Insemination or Embryo Transfer in Lactating Holstein Cows [PDF]
, 2007 D. Demetrio +3 more
openalex +1 more source
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Epidemiology of gastroschisis: A population-based study in California from 1995 to 2012. [PDF]
, 2018 BackgroundAlthough the incidence of gastroschisis is increasing, risk factors are not clearly identified.MethodsUsing the Linked Birth Database from the California Office of Statewide Health Planning and Development from 1995 to 2012, patients with ...
Anderson, Jamie E +6 more
core
The influence of the number of cocks on the conception rate among white leghorns
, 1972 G.C. Brantas +2 more
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Genetic parameters for conception rate and milk production traits within and across Holstein herds with different housing types and feeding systems during the first 3 lactations [PDF]
, 2020 Takeshi Yamazaki +4 more
openalex +1 more source