Results 71 to 80 of about 6,187,693 (341)

Effects of in utero heat stress on subsequent reproduction performance of first-calf Holstein heifers

open access: yesSpanish Journal of Agricultural Research, 2020
Aim of study: To determine the reproductive performance of heifers gestated under maternal conditions of heat stress in late gestation. Area of study: Northern Mexico (25° 32’ N, 103° 23’ W).
María I. Chavez   +5 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Conception architecturale d’un système mécatronique d’assistance à opérateur par Bond-Graph [PDF]

open access: yes, 2012
Les systèmes mécatroniques requièrent une forte intégration physique et fonctionnelle. Pour répondre au premier besoin, l’usage d’un outil de modélisation multi-physique tel que le Bond-Graph est nécessaire.
GOMAND, Julien   +3 more
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Incremental Learning of Variable Rate Concept Drift [PDF]

open access: yes, 2009
We have recently introduced an incremental learning algorithm, Learn + + .NSE, for N on-S tationary E nvironments, where the data distribution changes over time due to concept drift. Learn + + .NSE is an ensemble of classifiers approach, training a new classifier on each consecutive batch of data that become available, and combining them through an age-
Ryan Elwell, Robi Polikar
openaire   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

The Disjunctive Conception of Perceiving [PDF]

open access: yes, 2011
John McDowell's conception of perceptual knowledge commits him to the claim that if I perceive that P then I am in a position to know that I perceive that P. In the first part of this essay, I present some reasons to be suspicious of this claim - reasons
Haddock, Adrian, Adrian Haddock
core   +1 more source

FACTORS AFFECTING THE EFFICIENCY OF ARTIFICIAL INSEMINATION IN CATTLE AND BUFFALO IN PUNJAB, PAKISTAN

open access: yesPakistan Veterinary Journal, 2003
The main objective of this study was to identify the factors that affect the success of artificial insemination (A.I) services under field conditions. The data from a total of 459 inseminations were analyzed. The effects of farm, animal, semen/bull and A.
M. Anzar*, U. Farooq**, M.A. Mirza*, M. Shahab** and N. Ahmad*
doaj  

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