Results 91 to 100 of about 6,187,693 (341)
L’approche Living Lab : proposition et application d’une démarche méthodologique pour mieux prendre en compte les aspects humains dans la conception de produits logiciels [PDF]
Dans cet article, nous décrivons une démarche méthodologique de conception utilisant des technologies émergentes et s’inscrivant dans la continuité de l’approche Living Lab.
LOUP-ESCANDE, Emilie +3 more
core
The objectives of this study were to elucidate the impact of the administration of recombinant bovine somatotropin (rbST), in combination with Ovsynch protocol on the preovulatory follicle (POF) diameter, a daily growth rate of the dominant follicle (DF),
Mohamed Mohsen Mansour +1 more
doaj
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
The objective of this study was to determine the effects of the administration of recombinant bovine somatotropin (rbST) throughout lactation to high-yielding subfertile (conception > 270 days postpartum) Holstein cows undergoing extended lactations ...
Jessica Flores +5 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Conception rate is associated with a locus on chromosome 6.
A. The distribution of conception rate among cows (females). B. The distribution of conception rate among sires. C. Manhattan plots for the genome-wide screen for loci associated with conception rate. The dotted line represents the threshold for a genome-
Yusaku Gotoh (765852) +3 more
core +1 more source
Semen used for artificial insemination (AI) can be prepared in different ways, fresh extended fresh or chilled, or frozen-thawed (FT). The aim of the experiment was to evaluate the use of preserved semen to inseminate the oestrus mares.
R. I. Arifiantini +4 more
doaj
Effects of Semen Sexing Agent (Heifer-PlusTM) in Dairy Cow Reproduction
This study was conducted to investigate the use cryopreserved bovine sperm treated with Heifer-PlusTM Prefreeze kit and its effect on pregnancy rates calf sex ratio embryonic death, abortion, stillbirth and twinning rates in Holstein Friesian cows A ...
Constantin Găvan, Mihaela Riza
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source

