Results 111 to 120 of about 1,057,114 (308)

Relation between body condition score and conception rate of Japanese Black cows. [PDF]

Anim Biosci, 2023
Setiaji A, Oikawa T, Arakaki D.
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Monkey see monkey do:\ud A cognitive model to loss of free will\ud [PDF]

, 2012
Free will (if any) may be lost because of fear and our dependence on others. In this paper, we develop cognitive models to support this argument. We do not describe what free will is but what free will is not.
Mutaf, Asst. Prof Pars
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Ovarian response and conception rate in Boran and Boran*Holstein cows treated by Gonadotrophin-realizing hormone and ProstaglandinF2α with and without exogenous progesterone. [PDF]

BMC Vet Res, 2023
Ayanie TD, Wassie AT, Kebede EM, Mekonnen TY, Geleto TD, Biru AL.   +5 more
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Breeding practices and evaluation of hormonal estrus synchronization and mass artificial insemination of dairy cattle in southwest Ethiopia

Journal of Agriculture and Food Research
Estrus synchronization is the process of controlling or guiding a cow/heifer estrous cycle so that they can mate at roughly the same time. It may be used to increase the probability of detecting estrus, increase the rate of calving in response to feed ...
Worku Masho, Azmera Foato, Regasa Begna
doaj   +1 more source

Efficiency evaluation of two estrus synchronization protocols in estrus response and conception rate of dairy cows in the Dalocha district, Ethiopia. [PDF]

Heliyon, 2023
Haile SM, Abebe BK, Tesfa TW.
europepmc   +1 more source

Organic dairy cows: milk yield and lactation characteristics in thirteen established herds and development of a herd simulation model for organic milk production [PDF]

, 2001
As a consequence of organic standards and principles, organic dairy producers are frequently faced with a different set of management considerations than those found in conventional dairy systems.
Hovi, M
core