Results 121 to 130 of about 433,264 (313)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Efficiency evaluation of two estrus synchronization protocols in estrus response and conception rate of dairy cows in the Dalocha district, Ethiopia. [PDF]

Heliyon, 2023
Haile SM, Abebe BK, Tesfa TW.
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Effect of preovulatory follicle volume and serum oestradiol concentration on conception rate in postpartum Murrah buffaloes

, 2021
The oocytes recovered from large sized follicles have more potential for both meiotic and embryonic development, which helps in conception rate in cows and buffaloes. This investigation was carried out to study the effect of pre-ovulatory follicle volume,
Subramaniyan, Prakash, Mani, Selvaraju, Mahakrishnan, Palanisamy   +2 more
core  

Improvement of conception rate on Hanwoo; The key hormones and novel estrus detector. [PDF]

J Anim Sci Technol, 2021
Joo YH, Jeong SM, Paradhipta DHV, Lee HJ, Lee SS, Choi JS, Noh HT, Chang HH, Kim EJ, Kim SC.   +9 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Association of single nucleotide polymorphisms of PPP1R11 gene with conception rate in Karan Fries bull

, 2017
Bull fertility is an important component of reproductive efficiency in dairy cattle. PPP1R11 is a potent candidate gene for bull fertility being involved in the pathway of spermatogenesis.
Shabahat Mumtaz, Kaiser Parveen, Pooja Joshi, Alok Kumar Yadav, Anupama Mukherjee, Abdul Rahim, A. K. Gupta   +6 more
core   +1 more source

Breeding practices and evaluation of hormonal estrus synchronization and mass artificial insemination of dairy cattle in southwest Ethiopia

Journal of Agriculture and Food Research
Estrus synchronization is the process of controlling or guiding a cow/heifer estrous cycle so that they can mate at roughly the same time. It may be used to increase the probability of detecting estrus, increase the rate of calving in response to feed ...
Worku Masho, Azmera Foato, Regasa Begna
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

113 EFFECT OF SOME FACTORS ON CONCEPTION RATE IN ALPACAS UNDER PERUVIAN HIGHLAND CONDITION

, 2011
Alpacas are a domestic species of South American camelids with a great importance to highland people because of their high-quality fibre production. However, their reproductive performance has been reported to be poor, with a birth rate of 50% under ...
A. Ampuero, T. Huanca, A. Diaz, H. Huaman, W. Huanca, H. Diaz, D. Quispe, J. Camacho   +7 more
core   +1 more source