Results 101 to 110 of about 6,187,693 (341)

Du co-développement à la co-innovation - Analyse empirique des coopérations verticales en conception innovante [PDF]

open access: yes
Le secteur automobile est soumis depuis des décennies à deux tendances continues et a priori contradictoires : d'une part un mouvement de spécialisation / concentration qui tend à désintégrer la filière ; d'autre part une compétition par l'innovation où ...
Romain Beaume   +2 more
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Endocrine and ovarian responses in water buffalo cows immunized against inhibin and subjected to the Ovsynch protocol

open access: yesJournal of Integrative Agriculture, 2015
The aim of this study was to investigate the feasibility of stimulating ovarian follicle development in order to improve fertility in water buffalo cows by immunization against inhibin. The experiment was carried out in early summer (May) and included 24
Abdalla Bahareldin-Ali   +8 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Conception architecturale et biodiversité

open access: yes, 2018
Exploration des axes de travail contemporains dans l'intégration de la biodiversité dans la conception ...
Kunysz, Pavel
core  

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Explorative study of blood urea nitrogen (BUN), serum estrogen, and conception rate (CR) in small-scale dairy farms based on quantity of feed concentrate consumed by the cattle

open access: yesТеория и практика переработки мяса
The purpose of this study was to measure the level of BUN in dairy cows and its influence on services per conception (S/C) rate, milk output, and the forage to concentrate (F/C) ratio.
S. Mulyati   +14 more
doaj   +1 more source

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