Results 111 to 120 of about 2,817,688 (298)

Optimizing Market Scenarios for Battery Electric Vehicles Through a Machine Learning-Based Manufacturer Agent

open access: yesWorld Electric Vehicle Journal
To meet climate goals, the automotive industry is transitioning to electromobility, reshaping vehicle model variants, market composition and therefore influencing purchasing decisions.
Samuel Hasselwander   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Nitinol Design Concepts: May 2017

open access: yes, 2017
<p>This is the first release for the Nitinol Design Concepts project, providing a snapshot of this material at the time it was announced at the 2017 Shape Memory and Superelastic Technologies (SMST) conference and exhibition in San Diego, CA, May ...
Craig Bonsignore
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

The Congruence Between College Students’ Twitter Identities And Self-Concepts

open access: yes, 2017
The theories of imagined audiences, attention to social comparison information, and self-concept have been researched and verified with respect to individuals and their behaviors. However, no research has been conducted regarding the relationship between
Kara Lynn Carmichael (22015787)
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Political concepts /

open access: yes
"Written by a powerful international team of theorists, this book offers a sophisticated analysis of the central political concepts in the light of recent debates in political theory. All political argument employs political concepts.
Mason, Andreweditor.   +1 more
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Contextualizing concepts.

open access: yesCoRR, 2002
To cope with problems arising in the description of (1) contextual interactions, and (2) the generation of new states with new properties when quantum entities become entangled, the mathematics of quantum mechanics was developed. Similar problems arise with concepts.
Gabora, Liane, Aerts, Diederik
openaire   +4 more sources

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