Results 71 to 80 of about 2,174,067 (298)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
THE EFFECTIVENESS OF CREATIVE PROBLEM SOLVING ON LOGICAL THINKING ABILITY AND MASTERY OF CONCEPTS [PDF]
, 2020 This research aims to determine the effect of Creative Problem Solving (CPS) on logical thinking ability and concept achievement. The design was a nonequivalent pretest-posttest control group design.
lengkana, dewi +3 more
core +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
JPFT (Jurnal Pendidikan Fisika dan Teknologi), 2017 The purpose of this study is to examine the effect of using virtual laboratory in guided inquiry learning on studentsââ¬â¢ mastery concept of heat material.àThis study is quasi experiments with posttest only control group design.
Hermansyah Hermansyah +2 more
doaj +1 more source
Charles City landfill footprint
, 2020 /,_ ·- ·- --11 r -- j =-1 I AMERICAN LAND CONCEPTS 238 B MAIN STREET REISTERSTOWN, MARYLAND 21136 PHONE: (410) 526-2688 TOTAL PERMANENT IMPACTS: 3.31+/-Acres (144,120+/- SF) of nontidal forested wetlands and 150 LF (450 SF) of intermittent stream will ...
American Land Concepts;
core
Development of Student Worksheets Based on a Multi-Representation Approach to Improve Students' Mastery of Sound Wave Concepts [PDF]
, 2021 This development research aims to produce a product in the form of student worksheets based on a multi-representation approach to improve students' mastery of the sound wave concept that is valid, and effective.
Sutrio, Sutrio +2 more
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Indonesian Journal of Science and Mathematics Education, 2019 : The purpose of this study is to get an overview of the implementation of cognitive conflict approaches based on experimental methods on mastery of concepts and critical thinking skills. Quasi Experimental Design research design. The results showed that
Siti Masyuni, Ardian Asyhari
doaj +1 more source
ASSESING CRITICAL THINKING SKILLS AND MASTERY CONCEPTS: THE CASE OF ECOSYSTEM
, 2020 PENILAIAN KETERAMPILAN BERPIKIR KRITIS DAN PENGUASAAN KONSEP PADA MATERI EKOSISTEMAbstractCritical thinking skills and mastery concepts are competencies that measure cognitive aspects. Both of these competencies support each other.
Ristanto, Rizhal Hendi +2 more
core +1 more source