Results 51 to 60 of about 1,392,122 (268)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
, 2006 Over the last years, there has been a growing interest in the analysis of advertisements from the point of view of pragmatic theory (cf. Brierley, 1995; Myers, 1994; Rein, 1982; Tanaka, 1994).
Herrero Ruiz, Javier
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Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin +8 more
wiley +1 more source
A contrastive Study of Idiom and Metaphor Translation between English and Arabic [PDF]
مجلة الدراسات الإنسانية والأدبيةThis research studies the complexity of translating metaphors and idioms between Arabic and English. It mainly studies the accuracy and effectiveness of using cognitive theories such as conceptual Metaphor Theory and schema Theory to analyze the transfer
Ahmed Abdelmejid Ahmed Abdelmejid
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Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias +3 more
wiley +1 more source
, 2002 The cognitive operation of conceptual integration or blending as described by Fauconnier and Turner (1994,1996) includes the notion of emergent structure, that is to say, conceptual structure, which is part of the blend and which is independent and/or ...
Pérez Hernández, Lorena
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem +9 more
wiley +1 more source
Cognitive Studies | Études cognitives, 2018 The role of conceptual integration and simple dynamic scenarios in the meaning construction of the mapping in mathematics Over the last two decades the impact of conceptual metaphor and conceptual blending on mathematics has been extensively researched
Jacek Woźny
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, 2016 This work is partially supported by the COINVENT project (FET-Open grant number: 611553)
Confalonieri R. +5 more
openaire +4 more sources
CONCEPTUAL BLENDING IN HOUSE M.D. [PDF]
, 2011 The purpose of the present paper is to show how conceptual metaphor theory and blending theory or conceptual integration model can be complementary in analysis of language. We are going to discuss the language of the medical television series House M.D. (
Topolewska, Marta, Cichmińska, Monika
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