Results 151 to 160 of about 2,241,486 (282)

Emerging strategies to target metastasis and therapy resistance in melanoma

Molecular Oncology, EarlyView.
Emerging studies propose new approaches to interfere with melanoma progression. In recognition of melanoma awareness month, at Molecular Oncology, we highlight recently published research articles, focusing on novel therapeutic targets driving metastatic spread and outlining different strategies to overcome resistance to BRAF inhibitors and anti‐PD‐1 ...
Amel Aziba
wiley   +1 more source

Correction: Adolescent condom negotiation: a concept analysis and conceptual framework. [PDF]

Front Reprod Health
Antwi MA, Dogtir JD, Islam KAM, Alcena-Stiner DC.   +3 more
europepmc   +1 more source

A Conceptual Framework for Interpreting Recorded Human History [PDF]

Neither economics nor political science can explain the process of modern social development. The fact that developed societies always have developed economies and developed polities suggests that the connection between economics and politics must be a ...
Barry R. Weingast, Douglass C North, John Joseph Wallis   +2 more
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Human Values : A Conceptual Framework

NMIMS Management Review, 1992
N. B. Singh, S. K. Singh
doaj   +1 more source

The cardio-pancreatic axis in heart failure: from conceptual framework to empirical evidence. [PDF]

ESC Heart Fail
Dams OC, Vijver MAT, Verdonk RC, van Veldhuisen DJ.   +3 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Correction: Gender and mental health of adolescents: A conceptual framework developed in a Delphi study. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Saying "Yes" to Saying "No": A Conceptual Framework for Setting Boundaries in Plastic Surgical Practice. [PDF]

Plast Reconstr Surg Glob Open
Chandawarkar R, Pearson G, Krajewski A, Ladas S, Roy K.   +4 more
europepmc   +1 more source