Results 151 to 160 of about 6,381,927 (303)

Generativity: A systematic review and conceptual framework

International Journal of Management Reviews, 2021
Llewellyn D. W. Thomas, R. Tee
semanticscholar   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Ageing in Unani medicine: Conceptual framework and modulatory approaches. [PDF]

J Ayurveda Integr Med
Sameen A, Ali S, Rather F, Rasool I, Nayab H.   +4 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Digital Standardized Patients: Conceptual Framework for Generative AI-Empowered Medical Education. [PDF]

JMIR Med Educ
Jia C, Qi L.
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Human Values : A Conceptual Framework

NMIMS Management Review, 1992
N. B. Singh, S. K. Singh
doaj   +1 more source

Urban environmental exposure as a factor in adaptive neuromodulation: a conceptual framework. [PDF]

Front Hum Neurosci
Qamili A, Cenameri A.
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Colour-Guided Surgery: A Conceptual Framework for Multimodal Intraoperative Visualisation-A Narrative Review. [PDF]

Int J Med Robot
Nonaka T, Hashimoto S, Tominaga T, Yamashita M, Katayama H, Takamura Y, Yamaguchi S, Adachi T, Inoue Y, Matsumoto K.   +9 more
europepmc   +1 more source