Results 31 to 40 of about 2,253,125 (238)
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
A Conceptual Model for Scholarly Research Activity [PDF]
, 2010 This paper presents a conceptual model for scholarly research activity, developed as part of the conceptual modelling work within the ???Preparing DARIAH??? European e-Infrastructures project.
Benardou, Agiatis +3 more
core
International Journal of Computing, 2004 Decision making is mostly based on decision concepts and decision models built in decision support systems. Type of decision problem determines application. This paper presents a conceptual decision model that utilises rule- based methodologies, numerical algorithms and procedures, statistical methodologies including distributions, and visual support ...
openaire +4 more sources
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
Data and phenomena in conceptual modelling [PDF]
Synthese, 2009 The distinction between data and phenomena introduced by Bogen and Woodward (Philosophical Review 97(3):303-352, 1988) was meant to help accounting for scientific practice, especially in relation with scientific theory testing. Their article and the subsequent discussion is primarily viewed as internal to philosophy of science.
Thomas Müller +4 more
openaire +7 more sources
miRNA‐29 regulates epidermal and mesenchymal functions in skin repair
FEBS Letters, EarlyView.miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan +10 more
wiley +1 more source
The Conceptual LeanPPD Model [PDF]
, 2010 This paper is presenting the conceptual Lean Product and Process Development (LeanPPD) model which is a project funded by the EU-PF7. The project is addressing the needs of European manufacturing companies of a new model that goes beyond lean manufacturing, to ensure the transformation of the enterprise into lean environment.
Al-Ashaab, Ahmed +8 more
openaire +3 more sources
FEBS Letters, EarlyView.Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez +3 more
wiley +1 more source
Developing a conceptual model for exploring emergence [PDF]
, 2006 Emergence is a fundamental property of complex systems and can be thought of as a new property or behaviour which appears due to non-linear interactions within the system; emergence may be considered to be the 'product' or by-product of the system.
McDonald, D.M., Weir, G.R.S.
core +1 more source
A simple conceptual model of abrupt glacial climate events [PDF]
, 2007 Here we use a very simple conceptual model in an attempt to reduce essential parts of the complex nonlinearity of abrupt glacial climate changes (the so-called Dansgaard-Oeschger events) to a few simple principles, namely (i) a threshold process, (ii) an
Braun, H. +3 more
core +4 more sources