Results 51 to 60 of about 552,487 (315)

CONCEPTUAL DECISION MODEL

open access: yesInternational Journal of Computing, 2014
Decision making is mostly based on decision concepts and decision models built in decision support systems. Type of decision problem determines application. This paper presents a conceptual decision model that utilises rule- based methodologies, numerical algorithms and procedures, statistical methodologies including distributions, and visual support ...
openaire   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Improved staffing policies and practices in healthcare based on a conceptual model

open access: yesFrontiers in Public Health
BackgroundStaffing policies are critical in healthcare facilities. However, problems from a mismatch between staff numbers requirements and offers are frequently encountered.
Ning Wei   +6 more
doaj   +1 more source

Envisioning Adaptive Strategies to Change: Participatory Scenarios for Agropastoral Semiarid Systems in Nicaragua

open access: yesEcology and Society, 2011
Historically, the semiarid social-ecological systems of the dry Central American corridor have proven resilient to pressures. However, in the last century, these systems have experienced huge environmental and socioeconomic changes that have increased ...
Federica Ravera   +2 more
doaj   +1 more source

Conceptual Model for Knowledge Sharing Model in Creating Idea for Mobile Application

open access: yes, 2019
This study shows that several projects will be conducted at the workshop in which using the conceptual model for knowledge sharing approach to create an idea for mobile application.
Hussain, Hanafizan, Hanafizan Hussain
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Examining Crisis Communication in Geopolitical Conflicts: The Micro-Influencer Impact Model

open access: yesJournalism and Media
In the digital communication ecosystem, micro-influencers have influenced public response during crises, especially in complex geopolitical contexts. This paper introduces the micro-influencer impact model (MIIM), a framework for analyzing the impact of ...
Ahmed Taher   +2 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

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