Results 1 to 10 of about 1,910,103 (290)
TECHNOLOGY MODERNIZATION IN THE MINING SECTOR: MODELS AND EFFECTS
Север и рынок: формирование экономического порядка, 2023 Amidst the current shift towards sustainable development and a low-carbon economy, it is important to assess the preparedness of mining companies for implementing large-scale technology modernization programs.
Andrey Yu. Abrashitov +1 more
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Alzheimer’s & Dementia: Translational Research & Clinical InterventionsSocial determinants of health (SDOH), infections, and Alzheimer's disease and related dementias (ADRD) are interconnected through complex pathways. Existing research establishes associations between SDOH and infections, between SDOH and ADRD, and between
Juehyun Shin +2 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Bibliothecae.it, 2016 The adoption of new conceptual models for bibliographic and authority data, the latest normative structures of the catalogue, the language of data encoding and their communication in semantic Web, are some of the factors that are transforming library ...
Antonella Trombone
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In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The Comparison of the Efficieny of MCDM Models in site Selection of Flood Spread in GIS Environment (Case Studey: Garabaygan Catchment) [PDF]
نشریه جغرافیا و برنامهریزی, 2014 The selection of suitable location for implementing of flood spreading project and artificial recharge of aquifers is an important step. To assess this purpose, the Geographic Information System (GIS) conceptual models and decision making systems were ...
Hasan ali Faraji Sabokbar +3 more
doaj
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Development and application of a rainfall-runoff model for semi-arid regions
RBRH, 2020 Despite the advances undertaken in recent years, modeling watershed’s hydrological responses remains a complex task, especially in data-scarce areas. In order to overcome this, new models with distinct representations of hydrological processes continue ...
José Almir Cirilo +5 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source