Results 121 to 130 of about 2,525,798 (287)

Unifying Conceptual Spaces: Concept Formation in Musical Creative Systems

open access: yes, 2010
We examine Gärdenfors’ theory of conceptual spaces, a geometrical form of knowledge representation (Conceptual spaces: The geometry of thought, MIT Press, Cambridge, 2000), in the context of the general Creative Systems Framework introduced by Wiggins (J
Jamie Forth   +6 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Ontologies and Formation Spaces for Conceptual ReDesign of Systems

open access: yesActa Polytechnica, 2005
This paper discusses ontologies, methods for developing them and languages for representing them. A special ontology for computational support of the Conceptual ReDesign Process (CRDP) is introduced with a simple illustrative example of an application ...
J. Bíla, M. Tlapák
doaj  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Data Spaces’ synergies

open access: yes
This paper aims to shed light on the significance of synergies throughout the various stages of data space development and emphasizes the importance of considering data spaces as part of a broader development trajectory of the European data market.
Alonso, Daniel   +10 more
core   +2 more sources

A Cognitive Stylistic Analysis of Kofi Awoonor's The Weaver Bird

open access: yesJL3T (Journal of Linguistics, Literature and Language Teaching)
Colonial trauma has left a lasting imprint on postcolonial literature, shaping narratives of displacement, resistance, and cultural transformation. This study examines Kofi Awoonor's The Weaver Bird using a cognitive stylistic approach to uncover the ...
Cynthia Ma   +4 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

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