Results 61 to 70 of about 36,417 (176)
Studies of Proximity in Coworking Spaces: the Basic Conceptual Challenges
European Spatial Research and Policy, 2020 The article aims to identify main research challenges in studying coworking spaces (CSs) within the field of economic geography. It combines the perspective of proximity economics with the growing body of papers about spatial aspects of the operations of
Grzegorz Micek
doaj +1 more source
Applications of Conceptual Spaces [PDF]
, 2015 This volume provides an overview of applications of conceptual spaces theory, beginning with an introduction to the modeling tool that unifies the chapters. The first section explores issues of linguistic semantics, including speakers negotiation of meaning.
openaire +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Hacia un modelo de cambio conceptual: espacios controversiales y refocalización
Revista de Filosofia, 2005 A model of the dynamics of conceptual change in science and philosophy is proposed. It is assumed that even in revolutionary conceptual changes there is a web of continuities and discontinuities operating at the same time. Similarities and differences of
Óscar Nudler
doaj
Conceptual commentary of public spaces in Durban, South Africa
Town and Regional Planning, 2018 Within the context of African cities that are considered to have poor economic prospects and are failing its inhabitants, this article explores and assesses the quality of Durban’s open public spaces through a phenomenological lens, by applying the ...
Magdalena Cloete, Salena Yusuf
doaj +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Childhood Homes as Moral Spaces - New Conceptual Arena
Social Work and Society, 2011 In our western cultural imagery, the idea of home is deeply embedded in a static realm of childhood we take for granted: a permanent place of comfort, security, privacy, family and continuity.
Hannele Forsberg, Tarja Pösö
doaj +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source