Results 101 to 110 of about 345,125 (260)

An Exploration of Students’ Misconceptions about the Concept ‘Classification of Animals’ at Secondary Level and Effectiveness of Inquiry Method for Conceptual Change

open access: yesAnkara Üniversitesi Eğitim Bilimleri Fakültesi Dergisi, 2013
Research has provided overwhelming evidence that children enter in science classroom with ideas they have formed in making sense of the world around them.
Anjum NAZ, Abida NASREEN
doaj  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Dataset for measuring the conceptual understanding of optics in Rwanda. [PDF]

open access: yesF1000Res, 2021
Ndihokubwayo K   +3 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Effect of context based REACT strategy on students’ conceptual understanding of heredity

open access: yesCogent Education
The teaching of conceptual understanding is a key objective in the field of science education. But students, on average, do not adequately understand the concepts in a large number of science subjects.
Wuleta Ketema Abebe   +2 more
doaj   +1 more source

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