Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Molecular Oncology, EarlyView.Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson +11 more
wiley +1 more source
Addressing mathematics learning challenges through concept-based instruction
LUMATContinuous poor performance of learners in mathematics motivated the study reported in this paper. The purpose of the study was to investigate the challenges that concept-based instruction could address in trying to improve learners’ performance in ...
Mildret Ncube, Kakoma Luneta
doaj +1 more source
Editorial: Broadening our conceptual understanding of endogenous opioids in systems neuroscience. [PDF]
Front Syst Neurosci, 2023 Tejeda HA +3 more
europepmc +1 more source
Misconceptions in chemistry : a comparative study of Samoa and New Zealand high schools to identify their different origins and approaches to eliminate and correct them : a thesis presented in partial fulfilment of the requirements for the degree of Masters of Education at Massey University, Palmerston North, New Zealand [PDF]
, 2011 The report describes a comparative study of students' misconceptions. It does so by investigating year 13 students' conceptual understanding of the structure bonding and related properties of diamond and graphite. The aims of the case study are to elicit,
Suaalii, Faguele
core
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
The division of linguistic labour for offloading conceptual understanding. [PDF]
Philos Trans R Soc Lond B Biol Sci, 2023 Andrade-Lotero EJ +3 more
europepmc +1 more source
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Conceptual understanding in science learning and the role of four psychometric variables: a person-centered approach. [PDF]
Front Psychol, 2023 Vaiopoulou J +3 more
europepmc +1 more source
Understanding the Impact of a Community-led HIV Prevention Program in South Africa: Context, Conceptual Framework and Methodology [PDF]
, 1999 Catherine Campbell, Brian Williams
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An overview of conceptual understanding in science education curriculum in Indonesia
, 2018 The purpose of this article is to discuss the term of “conceptual understanding” in science education curriculum in Indonesia. The implementation of 2013 Curriculum focuses on the acquisition of contextual knowledge in respective areas and environments ...
A. Widiyatmoko*, K. Shimizu
semanticscholar +1 more source