Results 161 to 170 of about 7,797,471 (373)

The role of GeoGebra software in conceptual understanding and engagement among secondary school student

open access: yesInfinity
This study aims to identify the impact of GeoGebra software on conceptual understanding and engagement in the topic of Functions and Quadratic Equations in One Variable in high school.
Riyan Hidayat   +3 more
doaj   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

Development of Physics E-Learning Based on Discovery Learning to Improve Students' Conceptual Understanding and Learning Interest

open access: yesJurnal Teknologi Pendidikan
Thermodynamics material is abstract material that causes misconceptions. Misconceptions are caused by several things, one of which is the use of learning media that has not been maximized.
Juli Pratiwi, M. Rahmad, Syahril Syahril
doaj   +1 more source

Dataset for measuring the conceptual understanding of optics in Rwanda. [PDF]

open access: yesF1000Res, 2021
Ndihokubwayo K   +3 more
europepmc   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

open access: yesMolecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau   +9 more
wiley   +1 more source

An Exploration of Students’ Misconceptions about the Concept ‘Classification of Animals’ at Secondary Level and Effectiveness of Inquiry Method for Conceptual Change

open access: yesAnkara Üniversitesi Eğitim Bilimleri Fakültesi Dergisi, 2013
Research has provided overwhelming evidence that children enter in science classroom with ideas they have formed in making sense of the world around them.
Anjum NAZ, Abida NASREEN
doaj  

The need for a conceptual understanding of the macro and meso commercial determinants of health inequalities. [PDF]

open access: yesEur J Public Health, 2021
Maani N   +6 more
europepmc   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

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