Results 101 to 110 of about 1,698 (304)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Conceptual thinking for a conceptual project

open access: yesАрхитектон
The authors continue to develop and delve deeper into their ideas on conceptual design. Previously we examined the role and significance of a conceptual design within the framework of the antinomy "singular-universal" or, more specifically, "project - science".
Gushchin Alexander N.   +1 more
openaire   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

An Idea And An Image. The Iconoclastic Aspect Of Conceptualism

open access: yes, 2012
Conceptualism, as the art of an idea, placed itself beyond aesthetic and sensual experience. As a rule, it did not produce art objects which could be pleasing or that would represent reality.
Gralińska–Toborek, Agnieszka
core  

Re-examining Husserl’s Non-Conceptualism in the Logical Investigations [PDF]

open access: yes, 2019
A recent trend in Husserl scholarship takes the Logische Untersuchungen (LU) as advancing an inconsistent and confused view of the non-conceptual content of perceptual experience.
Kidd, Chad
core  

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Literatura postelektroniczna? Od literatury elektronicznej do kartki papieru, czyli podróż powrotna, z bagażem nowych doświadczeń

open access: yesAnnales Universitatis Paedagogicae Cracoviensis. Studia de Cultura, 2016
In my paper I am focusing on the impact of microcomputer revolution and network experiences (Internet) in contemporary verbal practices, including the development of electronic literature, and problems of the impact of recent experience of the media ...
Mikołaj Spodaryk
doaj  

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

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