Results 81 to 90 of about 1,698 (304)
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
, 2012 By accepting one of the definitions applied to conceptualism in the research on this genre, as art that “takes the form of objects under the condition that they have a secondary function in parallel with an idea” I draw attention to an exceptional ...
Kowalska, Bożena
core
Theoretical Dimension of Modern Designers’ Conceptual Forms of Creativity
Культура і мистецтво у сучасному світіThe aim of the article is to identify key characteristics of artistic and design practices interaction; to define directions of conceptual design development based on the results of analysing scientific and theoretical foundations of conceptualism as a ...
Oksana Lahoda
doaj +1 more source
Conceptual engineering: Conceptual innovation via conceptual refinement
MetaphilosophyAbstractMona Simion and Christoph Kelp (2020) have recently challenged the traditional conceptual engineering project. They defend a reorientation of this project that moves away from correcting conceptual shortcomings and emphasizes conceptual innovation instead. Central to their proposal is the role played by etiological functions.
openaire +1 more source
FEBS Open Bio, EarlyView.We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Two conceptions of conceptualism and nonconceptualism [PDF]
, 2006 Though it enjoys widespread support, the claim that perceptual experiences possess nonconceptual content has been vigorously disputed in the recent literature by those who argue that the content of perceptual experience must be conceptual content ...
T. M. Crowther, Crowther, Thomas
core +1 more source
Управление культуройThe article examines the phenomenon of text-centrism in Russian street art and analyzes the continuity between the conceptual art of the late Soviet period and contemporary street art.
Ulyana A. Vasilyeva
doaj +1 more source
Un sistema lógico de segundo orden conceptualista con operadores lambda ramificados
Crítica, 2018 We develop a second order logical system with ramified lambda operators, having ramified conceptualism as its philosophical background. Such a system is shown to relatively consistent.
Max A. Freund
doaj +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source