Results 71 to 80 of about 354 (266)
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Un sistema lógico de segundo orden conceptualista con operadores lambda ramificados
Crítica, 2018 We develop a second order logical system with ramified lambda operators, having ramified conceptualism as its philosophical background. Such a system is shown to relatively consistent.
Max A. Freund
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Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
THE IDEALIST VIEW OF DIVINE ACTION IN NATURE
Zygon, 2020 Theologies of divine action in nature have sought to maximize traction with the sciences to secure their credibility. While varying in significant ways, all extant proposals share a commitment to physical realism, the claim that (at least some) physical
doaj +2 more sources
Moscow Conceptualism in a Monologue with the Avant-garde [PDF]
Художественная культураThis article is the first to explore the relationship of Moscow conceptual artists with the creative and moral legacy of the Russian avant-garde of the 1910s-1920s.
Lazareva Ekaterina A.
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Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Colloquia Theologica Ottoniana, 2019 The first two parts of the article discuss the motivations leading to acceptance of the existence of universals, as well as their types. Four main positions in the so-called the dispute about universals are presented: conceptual realism (Platonism ...
Stanisław Judycki
doaj
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
HER2/neu-based vaccination with li-Key hybrid, GM-CSF immunoadjuvant and trastuzumab as a potent triple-negative breast cancer treatment. [PDF]
J Cancer Res Clin Oncol, 2023 Zhou Y.
europepmc +1 more source