Results 31 to 40 of about 1,026,899 (281)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Linguistic Personology and Linguistic Personality as Subjects of Vladimir V. Kolesov’s Scientific Reflection

СибСкрипт
Linguistic personology has remained a popular linguistic direction in Russia for more than thirty years. This discipline studies a native speaker or a linguistic personality with their own worldview, mentality, language fluency, linguistic creativity ...
Alexander V. Zagumennov
doaj   +1 more source

Негатив как содержательный концепт музыкальных сочинений XX - начала XXI веков

Вестник музыкальной науки, 2016
Статья посвящена одному из актуальных для современного музыкального искусства содержательных концептов - негативу, формирующемуся благодаря использованию композиторами таких образных категорий, как война, природные стихии с их трагическими последствиями,
Петров, Владислав Олегович
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Modern Artistic Space: the Problem of Anthropological and Aesthetic Transformation

Дискурс
Introduction. The problem of analyzing the contemporary artistic space has its own evolution, its genesis is reduced to understanding different kinds of transformations in relation to the traditional art as a form of creative perception of reality based ...
E. A. Kapichina
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Onto-semantyczny wymiar sporu o istnienie treści niepojęciowej (Controversy over the existence of non-conceptual content. Ontological and semantic approach) [PDF]

Analiza i Egzystencja, 2010
In his seminal book (Mind and World) John McDowell argues against the widely spread claim of empiricists that content of experience might be non-conceptual.
Sebastian Tomasz Kołodziejczyk
doaj  

Value Pluralism of International Intellectual Property Law [PDF]

Faṣlnāmah-i Pizhūhish-i Huqūq-i Khuṣūṣī, 2019
Most theorists of IP law have attempted to justify intellectual property rights in preserving one particular value as a super value. The dominant view is that international IP law aims to maximize economic efficiency through incentivizing creation and ...
Tayebeh Saheb
doaj   +1 more source