Results 61 to 70 of about 1,966,627 (313)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Security Conceptualization [PDF]

open access: yes, 2016
In the past, all human beings lived under the traditional concept of „security‟: every state endeavors to protect itself from enemy states. Absolutely, „security‟ is postured by the military power of a state.
Nyein Nyein San Ei
core  

Conceptualization of WTP-answers.

open access: yes, 2019
Conceptualization of WTP-answers.
Ulrich J. Frey (5628794)   +1 more
core   +1 more source

Modelling domain knowledge using explicit conceptualization [PDF]

open access: yes, 1994
Applications are characterized by the tasks and domains involved. Knowledge modeling can be divided into two conceptual subactivities: modeling the task and modeling the domain knowledge. An explicit conceptualization of the domain knowledge at the heart
Abu-Hanna, A.   +3 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Ethical Leadership: Conceptualization and Measurement

open access: yes, 2017
The construct of ethical leadership has garnered much research attention in recent years. However, researchers have not reached consensus on the conceptualization and measurement of ethical leadership.
Sun, Jianmin, Lu, X
core  

Peace with Adjectives: Conceptual Fragmentation or Conceptual Innovation?

open access: yesInternational Studies Review
Abstract What strategies can be employed to conceptualize peace? In recent years, scholars have introduced an impressive array of “peace with adjectives” in order to make sense of some of the normative and empirical underpinnings of peace.
Simon Pierre Boulanger Martel   +5 more
openaire   +3 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Conceptual Engineering and Conceptual Ethics

open access: yes, 2020
Conceptual engineering is a branch of philosophy that is concerned with assessing representational devices such as concepts and words. Conceptual engineers looks for the problems with such devices and attempt to come up with ways of improving flawed concepts: they attempt to say how those concepts should be. This is the first volume devoted entirely to
openaire   +3 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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